Description

1-Nitro-3-(Trifluoromethane)Sulfonylbenzene is a high-value, multi-functional aromatic building block characterized by its electron-deficient nitro and strongly electron-withdrawing triflyl substituents. This unique combination of functional groups makes it an indispensable intermediate for the synthesis of complex molecules in advanced research and industrial chemistry. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors for constructing novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring sulfonamide or trifluoromethylsulfonyl pharmacophores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the triflyl group can enhance biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers, liquid crystals, and electronic materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution reactions due to the activating nitro group.
• Ligand and Catalyst Development: Useful for creating novel ligands for metal catalysis and organocatalysts in asymmetric synthesis.
• Dye and Pigment Intermediate: Acts as a precursor in the synthesis of specialized dyes and pigments with unique colorfastness or electronic properties.

Basic Information

Product Name	1-Nitro-3-(Trifluoromethane)Sulfonylbenzene
CAS No.	1548-72-7
Molecular Formula	C7H4F3NO4S
Molecular Weight	255.17 g/mol
Synonyms	3-Nitrobenzenesulfonyl Trifluoride; 3-Nitro-α,α,α-trifluorobenzenemethanesulfonate; 1-Nitro-3-(trifluoromethylsulfonyl)benzene; m-Nitrobenzenesulfonyl Trifluoride; 3-(Trifluoromethanesulfonyl)nitrobenzene; Benzenesulfonyl fluoride, 3-nitro-, trifluoro derivative; 3-Nitrobenzotrifluoride sulfone
EINECS	Contact for details

Quality Control

Every batch of 1-Nitro-3-(Trifluoromethane)Sulfonylbenzene is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is 2-8°C for long-term stability. The compound is compatible with strong acid/organic solvent environments but should be handled with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.