Description

5-Bromo-2-(Trifluoromethyl)Benzamide is a high-purity, versatile organic building block characterized by its bromine and trifluoromethyl substituents. This compound is valued for its role as a critical intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for the synthesis of organic electronic materials, liquid crystals, and advanced polymers.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl structures.
• Chemical Biology & Proteomics: Utilized as a building block for designing molecular probes, enzyme inhibitors, and labeled compounds for biochemical studies.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-Bromo-2-(Trifluoromethyl)Benzamide
CAS No.	1548-16-9
Molecular Formula	C8H5BrF3NO
Molecular Weight	268.03 g/mol
Synonyms	5-Bromo-2-(trifluoromethyl)benzamide; 2-Trifluoromethyl-5-bromobenzamide; Benzamide, 5-bromo-2-(trifluoromethyl)-; 1548-16-9; 5-Bromo-alpha,alpha,α-trifluoro-o-toluamide; 5-Bromo-2-trifluoromethylbenzamide
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Trifluoromethyl)Benzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.