Description

3-(4-Fluoro-Phenyl)-2-Thioxo-2,3-Dihydro-1H-Quinazolin-4-One is a high-purity, advanced pharmaceutical intermediate belonging to the quinazolinone class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific therapeutic pathways. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for drug discovery and development programs. The consistent quality and reliable supply of this intermediate are essential for ensuring the reproducibility and scalability of complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those with quinazolinone-based structures for oncology, CNS, or anti-inflammatory applications.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for medicinal chemistry, enabling the exploration of structure-activity relationships (SAR) through further functionalization.
• Academic & R&D Laboratories: Employed in fundamental research to study heterocyclic chemistry, reaction mechanisms, and to develop new synthetic methodologies.
• Material Science Precursor: Potential use in the development of organic electronic materials or ligands for catalytic systems due to its conjugated system and donor-acceptor properties.

Basic Information

Product Name	3-(4-Fluoro-Phenyl)-2-Thioxo-2,3-Dihydro-1H-Quinazolin-4-One
CAS No.	1547-15-5
Molecular Formula	C14H9FN2OS
Molecular Weight	272.30 g/mol
Synonyms	4(3H)-Quinazolinone, 3-(4-fluorophenyl)-2-thioxo-; 3-(4-Fluorophenyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one; 3-(p-Fluorophenyl)-2-thioxo-1,2-dihydro-4(3H)-quinazolinone; 2-Thioxo-3-(4-fluorophenyl)-1,2,3,4-tetrahydro-4-quinazolinone; 1547-15-5; 3-(4-Fluorophenyl)-2-sulfanylidene-1H-quinazolin-4-one
EINECS	Contact for details

Quality Control

Our 3-(4-Fluoro-Phenyl)-2-Thioxo-2,3-Dihydro-1H-Quinazolin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assay and identity confirmation, to ensure it meets exacting specifications for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.