Description

2,5-Difluoro-4-Nitroaniline is a high-purity aromatic amine derivative characterized by its distinct fluorine and nitro substituents, making it a valuable and versatile building block in advanced chemical synthesis. Its primary value lies in its role as a key intermediate for the production of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research and development chemists, process engineers, and manufacturers in industries requiring fluorinated fine chemicals, such as active pharmaceutical ingredient (API) development, crop protection agents, and specialty dye synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system disorders and anti-infectives.
• Agrochemical Synthesis: Serves as a key building block for developing novel herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental stability.
• Dye and Pigment Manufacturing: Used in the production of specialized azo dyes and pigments, where the nitro and amino groups facilitate chromophore formation.
• Liquid Crystal & Electronic Materials: Acts as an intermediate in the synthesis of fluorinated compounds for liquid crystal displays (LCDs) and other electronic applications.
• Organic Synthesis & Research: A versatile reagent in academic and industrial R&D for constructing complex heterocycles and fluorinated aromatic systems.
• Cross-Coupling Reactions: The aniline functionality makes it a suitable substrate for palladium-catalyzed cross-coupling reactions to create biaryl structures.

Basic Information

Product Name	2,5-Difluoro-4-Nitroaniline
CAS No.	1542-36-5
Molecular Formula	C6H4F2N2O2
Molecular Weight	174.11 g/mol
Synonyms	4-Nitro-2,5-difluoroaniline; 2,5-Difluoro-4-nitrobenzenamine; 1-Amino-2,5-difluoro-4-nitrobenzene; Benzenamine, 2,5-difluoro-4-nitro-; 2,5-Difluoro-4-nitro-phenylamine; 4-Amino-3,6-difluoronitrobenzene; 2,5-Difluoroaniline, 4-nitro-
EINECS	Contact for details

Quality Control

Our 2,5-Difluoro-4-Nitroaniline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet exacting customer specifications. Certificates of Analysis (COA) detailing purity, identity, and related substances are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.