Description

4-(Diethoxyphosphinyl)Benzoic Acid is a high-value organophosphorus intermediate characterized by its benzoic acid core functionalized with a diethoxyphosphinyl group. This unique structure makes it a critical building block for synthesizing advanced materials and active pharmaceutical ingredients (APIs). It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate phosphonate functionalities into complex molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting bone diseases, enzyme inhibition, or acting as prodrugs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, plant growth regulators, and pesticides with phosphonate activity.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized phosphonate-based ligands used in metal catalysis and coordination chemistry.
• Material Science: Building block for functionalized polymers, metal-organic frameworks (MOFs), and surface modification agents.
• Chemical Research: Valuable reagent in organic synthesis for introducing the phosphonic acid ester group onto aromatic systems under mild conditions.
• Peptide Mimetics: Employed in the design and synthesis of phosphonate-containing peptide analogs for biochemical studies.

Basic Information

Product Name	4-(Diethoxyphosphinyl)Benzoic Acid
CAS No.	1527-34-0
Molecular Formula	C11H15O5P
Molecular Weight	258.21 g/mol
Synonyms	4-(Diethoxyphosphoryl)benzoic acid; Benzoic acid, 4-(diethoxyphosphinyl)-; Diethyl (4-carboxyphenyl)phosphonate; (4-Carboxyphenyl)phosphonic acid diethyl ester; p-(Diethoxyphosphinyl)benzoic acid; 4-Carboxyphenylphosphonic acid diethyl ester; Diethyl 4-carboxybenzylphosphonate; 1527-34-0
EINECS	Contact for details

Quality Control

Our 4-(Diethoxyphosphinyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.