Description

1-Oxopropylphosphonic Acid Diethyl Ester is a versatile organophosphorus compound that serves as a key intermediate in the synthesis of complex molecules. Its value lies in its ability to act as a reactive building block for introducing phosphonate and ketone functionalities, enabling the development of advanced materials and active ingredients. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active compounds or functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require phosphonate moieties.
• Ligand and Catalyst Precursor: Serves as a starting material for creating specialized phosphonate-based ligands used in homogeneous catalysis and metal complexation.
• Material Science Research: Employed in the development of flame retardants, polymer modifiers, and specialty additives where phosphonate groups enhance material properties.
• Organic Synthesis Reagent: Functions as a reagent in Horner-Wadsworth-Emmons (HWE) olefination reactions and other carbon-carbon bond-forming processes.

Basic Information

Product Name	1-Oxopropylphosphonic Acid Diethyl Ester
CAS No.	1523-68-8
Molecular Formula	C7H15O4P
Molecular Weight	194.16 g/mol
Synonyms	Diethyl (1-oxopropyl)phosphonate; Diethyl 1-oxopropylphosphonate; Diethyl propanoylphosphonate; Propanoylphosphonic Acid Diethyl Ester; 3-Oxo-propylphosphonic Acid Diethyl Ester; 1-Oxo-1-propylphosphonic Acid Diethyl Ester; β-Ketophosphonate; CAS 1523-68-8
EINECS	216-195-8

Quality Control

Our 1-Oxopropylphosphonic Acid Diethyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.430 - 1.440
Density (20°C)	1.10 - 1.20 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.