Description

α-Cyano-4-Methoxycinnamic Acid is a high-purity, crystalline organic compound belonging to the cinnamic acid derivative family. This specialized chemical serves as a critical matrix material for Matrix-Assisted Laser Desorption/Ionization (MALDI) mass spectrometry, enabling the sensitive analysis of proteins, peptides, and other biomolecules. It is essential for research and quality control laboratories in the pharmaceutical, biotechnology, and academic sectors requiring precise analytical characterization.

Application

• Primary Matrix for MALDI-TOF Mass Spectrometry: Used extensively as a matrix compound for the analysis of proteins, peptides, oligonucleotides, and synthetic polymers.
• Proteomics and Biomarker Research: Facilitates the identification and characterization of proteins and peptides in complex biological samples.
• Pharmaceutical Quality Control: Employed in the analysis of active pharmaceutical ingredients (APIs), impurities, and biopharmaceuticals.
• Synthetic Intermediate: Serves as a building block in organic synthesis for creating more complex molecules with potential biological activity.
• Material Science Research: Investigated for its photophysical properties and potential applications in organic electronic materials.

Basic Information

Product Name	α-Cyano-4-Methoxycinnamic Acid
CAS No.	1519-55-7
Molecular Formula	C11H9NO3
Molecular Weight	203.19 g/mol
Synonyms	α-Cyano-4-hydroxycinnamic acid methyl ether; 4-Methoxy-α-cyanocinnamic acid; (E)-2-Cyano-3-(4-methoxyphenyl)acrylic acid; 3-(4-Methoxyphenyl)-2-cyanoacrylic acid; Cinnamic acid, α-cyano-4-methoxy-; trans-α-Cyano-4-methoxycinnamic acid; MALDI Matrix CHCA analog; 4-Methoxy-α-cyanocinnamate
EINECS	216-179-8

Quality Control

Our α-Cyano-4-Methoxycinnamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, to ensure it meets the high standards required for sensitive analytical applications like MALDI-TOF MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	215 - 220 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.