Description

2-Phenylbutyric Acid Anhydride is a high-purity organic anhydride derivative of 2-phenylbutyric acid, serving as a versatile and reactive intermediate in advanced chemical synthesis. Its primary value lies in its ability to act as an acylating agent, facilitating the efficient introduction of the 2-phenylbutyryl moiety into target molecules under controlled conditions. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used in the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators requiring the phenylbutyric acid structure.
• Polymer Chemistry: Acts as a monomer or modifier in the production of specialty polyesters and polyamides with enhanced properties.
• Fine Chemical Production: Employed as an acylating agent in the manufacture of dyes, fragrances, and liquid crystal compounds.
• Biochemical Research: Useful in proteomics and peptide synthesis for modifying amino acid side chains.
• Organic Synthesis Reagent: Serves as a versatile reagent for esterification and amidation reactions in complex molecule construction.

Basic Information

Product Name	2-Phenylbutyric Acid Anhydride
CAS No.	1519-21-7
Molecular Formula	C20H22O3
Molecular Weight	310.39 g/mol
Synonyms	2-Phenylbutanoic Anhydride; α-Phenylbutyric Anhydride; Butanoic acid, 2-phenyl-, anhydride; (2-Phenylbutyryl) oxide; Diphenylbutyric Anhydride; 2-Phenylbutyryl Anhydride; Butyric acid, 2-phenyl-, anhydride
EINECS	Contact for details

Quality Control

Our 2-Phenylbutyric Acid Anhydride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography and spectroscopy, to confirm identity and meet stringent impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support compliance with major regulatory frameworks, including REACH, and can supply materials suitable for cGMP manufacturing upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, strong oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.