Description

17-Alpha,21-Dihydroxy-5-β-Pregnane-3,11,20-Trione 21-Acetate is a high-purity steroid derivative and a key synthetic intermediate in pharmaceutical manufacturing. Its precise molecular structure makes it a critical building block for the development of active pharmaceutical ingredients (APIs), particularly corticosteroids and other therapeutic agents. This compound is essential for research and production facilities in the pharmaceutical, biotechnology, and fine chemical sectors that require reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of corticosteroid drugs and other steroid-based therapeutics.
• Biochemical Research: Used as a reference standard or starting material in metabolic pathway studies and steroid hormone research.
• Fine Chemical Synthesis: Serves as a specialized building block for creating novel chemical entities in medicinal chemistry.
• API Development: Integral to the research and development process for new Active Pharmaceutical Ingredients targeting inflammation and hormonal regulation.

Basic Information

Product Name	17-Alpha,21-Dihydroxy-5-β-Pregnane-3,11,20-Trione 21-Acetate
CAS No.	1499-59-8
Molecular Formula	C23H32O7
Molecular Weight	420.50 g/mol
Synonyms	21-Acetoxy-17α,21-dihydroxy-5β-pregnane-3,11,20-trione; 17α,21-Dihydroxy-5β-pregnane-3,11,20-trione 21-acetate; 5β-Pregnane-3,11,20-trione, 17,21-dihydroxy-, 21-acetate, (17α)-; Reichstein's Substance L 21-Acetate; 11-Dehydrocorticosterone 21-acetate (5β-isomer); 17-Hydroxy-11-dehydrocorticosterone 21-acetate (5β); 5β-Dihydrocortisone 21-acetate
EINECS	Contact for details

Quality Control

Our 17-Alpha,21-Dihydroxy-5-β-Pregnane-3,11,20-Trione 21-Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.