Description

Isopropylphosphonothioic Dichloride is a highly reactive organophosphorus intermediate characterized by its dichloride and thiophosphoryl functional groups. This compound is critical for the synthesis of advanced thiophosphonate derivatives, which are key building blocks in agrochemical and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the fine chemical, crop protection, and specialty materials industries seeking to introduce specific phosphorus-containing motifs into their target molecules.

Application

• Agrochemical Intermediate: A key precursor for the synthesis of novel insecticides, herbicides, and fungicides containing thiophosphonate ester groups.
• Pharmaceutical Building Block: Used in medicinal chemistry for the development of potential drug candidates, including enzyme inhibitors and bioactive probes.
• Ligand Synthesis: Serves as a starting material for creating specialized phosphine-thioate ligands used in catalysis and metal complexation.
• Flame Retardant Development: Employed in research to develop new organophosphorus compounds for flame-retardant applications in polymers and materials.
• Chemical Research & Development: A versatile reagent for academic and industrial labs exploring new reactions in organophosphorus chemistry.
• Specialty Chemical Production: Used in the manufacture of custom thiophosphonic acids and their derivatives for various industrial applications.

Basic Information

Product Name	Isopropylphosphonothioic Dichloride
CAS No.	1498-60-8
Molecular Formula	C3H7Cl2OPS
Molecular Weight	193.03 g/mol
Synonyms	Isopropylphosphonothioic Dichloride; Isopropylphosphonothioyl Dichloride; Propan-2-ylphosphonothioic Dichloride; Isopropyl Thiophosphonic Dichloride; (Isopropyl)phosphonothioic Dichloride; Phosphonothioic Dichloride, Isopropyl-; 1498-60-8; Isopropylphosphonochloridothioate
EINECS	Contact for details

Quality Control

Our Isopropylphosphonothioic Dichloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and synthesis. Each lot is analyzed using advanced techniques including GC, NMR, and titration to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical properties is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.35 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.