Description

Methyl 2-(7-Nitro-1H-Indol-3-Yl)Acetate is a specialized nitro-substituted indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized indole scaffold essential for constructing complex molecules with potential biological activity. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for use in medicinal chemistry programs and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new indole-based therapeutic agents.
• Agrochemical Development: Intermediate in the research and production of advanced pesticides and herbicides that utilize the indole nucleus.
• Organic Synthesis: Versatile precursor for further functionalization, including reduction of the nitro group or hydrolysis of the ester to access carboxylic acid derivatives.
• Biochemical Probe Synthesis: Used to create labeled compounds or probes for studying biological systems and enzyme interactions.

Basic Information

Product Name	Methyl 2-(7-Nitro-1H-Indol-3-Yl)Acetate
CAS No.	1496-81-7
Molecular Formula	C11H10N2O4
Molecular Weight	234.21 g/mol
Synonyms	Methyl (7-Nitro-1H-indol-3-yl)acetate; 3-Indoleacetic acid, 7-nitro-, methyl ester; Methyl 7-nitroindol-3-ylacetate; 7-Nitroindole-3-acetic acid methyl ester; 1496-81-7; Methyl 2-(7-nitro-1H-indol-3-yl)acetate; (7-Nitro-1H-indol-3-yl)acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-(7-Nitro-1H-Indol-3-Yl)Acetate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.