Description

Cyclopropylcarbonylphosphonic Acid Diethyl Ester is a high-value organophosphorus building block essential for advanced chemical synthesis. This compound is prized for its unique cyclopropyl and phosphonate ester functionalities, which enable the construction of complex molecular architectures. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the cyclopropyl moiety.
• Chemical Research & Development: Serves as a versatile reagent in organic synthesis, particularly in Horner-Wadsworth-Emmons (HWE) olefination reactions to form carbon-carbon double bonds.
• Material Science Precursor: Employed in the development of specialized polymers, ligands for catalysis, and other functional materials.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	Cyclopropylcarbonylphosphonic Acid Diethyl Ester
CAS No.	1489-91-4
Molecular Formula	C9H17O4P
Molecular Weight	220.20 g/mol
Synonyms	Diethyl (cyclopropylcarbonyl)phosphonate; Diethyl Cyclopropylcarbonylphosphonate; Cyclopropanecarbonylphosphonic Acid Diethyl Ester; (Cyclopropylcarbonyl)phosphonic Acid Diethyl Ester; Diethyl Cyclopropanecarbonylphosphonate; (Diethoxyphosphinyl)cyclopropylmethanone; Cyclopropylcarbonylphosphonate Diethyl Ester
EINECS	Contact for details

Quality Control

Our Cyclopropylcarbonylphosphonic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support development and commercial projects requiring compliance with various pharmacopeial or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.