Description

3-Phenyl-3-Pyrrolidinol Hcl is a versatile chiral building block and intermediate of significant importance in synthetic organic chemistry. Its pyrrolidine core and phenyl substituent make it a valuable scaffold for constructing complex molecules with specific stereochemistry. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals. Its utility stems from its ability to introduce both a nitrogen-containing heterocycle and an aromatic moiety into target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic and R&D Laboratories: Utilized in methodological studies and the exploration of new synthetic pathways in organic chemistry.

Basic Information

Product Name	3-Phenyl-3-Pyrrolidinol Hcl
CAS No.	1488-02-4
Molecular Formula	C10H13NO • HCl
Molecular Weight	199.68 g/mol
Synonyms	3-Phenyl-3-pyrrolidinol hydrochloride; 3-Phenylpyrrolidin-3-ol hydrochloride; (3R)-3-Phenyl-3-pyrrolidinol hydrochloride (if applicable to specific enantiomer); (3S)-3-Phenyl-3-pyrrolidinol hydrochloride (if applicable to specific enantiomer); 3-Hydroxy-3-phenylpyrrolidine hydrochloride; Pyrrolidin-3-ol, 3-phenyl-, hydrochloride; 1-Aza-3-phenylbicyclo[3.1.0]hexan-3-ol hydrochloride (possible bicyclic form).
EINECS	Contact for details

Quality Control

Our 3-Phenyl-3-Pyrrolidinol Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions if the container is opened frequently to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (for enantiopure grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.