Description

1,1,4,4-Tetraphenyl-2-Butyn-1,4-Diol is a high-value, symmetrical diol featuring a central butynyl linker flanked by four phenyl groups. This unique molecular architecture makes it a versatile and critical building block in advanced organic synthesis and materials science. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those requiring rigid, sterically hindered diol functionalities.
• Ligand Synthesis: Used to prepare sophisticated chiral and achiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Acts as a monomer or chain extender in the production of specialty polyesters, polyurethanes, and high-performance resins with enhanced thermal stability.
• Material Science Research: Employed in the development of organic electronic materials, such as hole-transport layers or non-linear optical (NLO) materials.
• Agrochemical Synthesis: Utilized as an intermediate for creating novel active ingredients with specific steric and electronic properties.
• Cross-coupling Reactions: Functions as a substrate or precursor in Sonogashira, Heck, and other palladium-catalyzed coupling reactions to build conjugated systems.

Basic Information

Product Name	1,1,4,4-Tetraphenyl-2-Butyn-1,4-Diol
CAS No.	1483-74-5
Molecular Formula	C28H22O2
Molecular Weight	390.48 g/mol
Synonyms	1,1,4,4-Tetraphenylbut-2-yne-1,4-diol; Tetraphenylbutynediol; 2-Butyne-1,4-diol, 1,1,4,4-tetraphenyl-; 1,4-Dihydroxy-1,1,4,4-tetraphenyl-2-butyne; α,α,α',α'-Tetraphenyl-2-butyn-1,4-diol
EINECS	Contact for details

Quality Control

Our 1,1,4,4-Tetraphenyl-2-Butyn-1,4-Diol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	168 - 172 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.