Description

Benzoyl-L-Leucine is a high-purity, protected amino acid derivative essential for advanced peptide synthesis and pharmaceutical research. Its primary value lies in serving as a crucial chiral building block, enabling the controlled introduction of the leucine moiety while protecting the reactive amine group. This compound is critically needed by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in the production of bioactive peptides, APIs, and novel therapeutic agents.

Application

• Peptide Synthesis: A key chiral intermediate for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics.
• Pharmaceutical Intermediates: Used in the research and development of Active Pharmaceutical Ingredients (APIs) and prodrugs.
• Biochemical Research: Employed as a substrate or standard in enzymatic studies and metabolic pathway investigations.
• Fine Chemical Production: Serves as a specialized building block for custom synthesis and contract manufacturing.
• Protecting Group Chemistry: Utilized in multi-step organic syntheses where temporary protection of the amino functionality is required.

Basic Information

Product Name	Benzoyl-L-Leucine
CAS No.	1466-83-7
Molecular Formula	C₁₃H₁₇NO₃
Molecular Weight	235.28 g/mol
Synonyms	N-Benzoyl-L-leucine; (S)-2-Benzamido-4-methylpentanoic acid; L-Leucine, N-benzoyl-; Bz-Leu-OH; N-α-Benzoyl-L-leucine; Benzoylleucine; NSC 3349; Benzoic acid, (1-carboxy-4-methylpentyl)amide, L-
EINECS	215-979-4

Quality Control

Our Benzoyl-L-Leucine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.