Description

1-(5-Chloro-2-Hydroxyphenyl)Ethanone is a versatile chlorinated aromatic ketone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a phenolic hydroxyl and an acetyl group on a chlorinated benzene ring, makes it a valuable building block for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with anti-inflammatory, antibacterial, or central nervous system activity.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, leveraging its chlorophenol backbone.
• Dye and Pigment Manufacturing: Serves as a starting material for synthesizing specialized azo dyes and complex organic pigments.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for constructing benzofuran, chromone, and other heterocyclic frameworks.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal-catalyzed coupling reactions due to its chelating potential.
• UV Absorber & Stabilizer Precursor: Intermediate in the production of compounds used as light stabilizers in polymers and coatings.

Basic Information

Product Name	1-(5-Chloro-2-Hydroxyphenyl)Ethanone
CAS No.	1450-74-4
Molecular Formula	C8H7ClO2
Molecular Weight	170.59 g/mol
Synonyms	5'-Chloro-2'-hydroxyacetophenone; 2-Acetyl-4-chlorophenol; 1-(5-Chloro-2-hydroxyphenyl)ethan-1-one; 4-Chloro-2-hydroxyacetophenone; 5-Chloro-2-hydroxyacetophenone; NSC 403697; 2-Hydroxy-5-chloroacetophenone
EINECS	215-909-4

Quality Control

Our production of 1-(5-Chloro-2-Hydroxyphenyl)Ethanone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is manufactured in facilities operating under cGMP principles where applicable. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.