Description

1,2-Dichloro-4-Fluorobenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers engaged in creating active pharmaceutical ingredients (APIs), crop protection agents, and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), especially those containing fluorinated and chlorinated aromatic systems.
• Agrochemical Synthesis: Used in the manufacturing of advanced herbicides, fungicides, and insecticides, where the fluorine and chlorine atoms enhance biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated liquid crystal compounds and organic light-emitting diode (OLED) materials, contributing to improved electronic properties.
• Specialty Polymer Monomer: Employed in the production of high-performance polymers and resins with specific thermal and chemical resistance properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new reaction pathways and creating novel fluorinated compounds.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex dyes and organic pigments, where halogen atoms influence color fastness and hue.

Basic Information

Product Name	1,2-Dichloro-4-Fluorobenzene
CAS No.	1435-49-0
Molecular Formula	C6H3Cl2F
Molecular Weight	164.99 g/mol
Synonyms	4-Fluoro-1,2-dichlorobenzene; 1,2-Dichloro-4-fluorobenzene; 3,4-Dichlorofluorobenzene; Benzene, 1,2-dichloro-4-fluoro-; 4-Fluorobenzene-1,2-dichloride; 1,2-Dichloro-4-fluoro-benzene; o-Dichloro-p-fluorobenzene
EINECS	215-859-7

Quality Control

Our 1,2-Dichloro-4-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including Gas Chromatography (GC) and Nuclear Magnetic Resonance (NMR), to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee compliance with your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Density (at 20°C)	~1.45 g/cm³
Boiling Point	~185-190 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.