Description

(2R)-3,3'Aβ,6',6',9'Aβ-Pentamethyl-3'A,4',5',5'Aα,6',7',8',9',9'A,9'Bα-Decahydrospiro[Furan-2(5H),2'(1'H)-Naphtho[2,1-B]Furan]-5-One is a high-purity, stereochemically defined spirocyclic furanone compound. This complex molecule serves as a critical chiral intermediate or building block in advanced organic synthesis, particularly for pharmaceuticals and fine chemicals. It is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise molecular architecture for creating novel active compounds.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry impacts biological activity.
• Fine Chemical Production: Serves as a precursor for complex fragrance and flavor molecules, or other high-value specialty chemicals.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including asymmetric synthesis and spirocycle formation.
• Material Science Research: Potential monomer or precursor for developing specialized polymers with unique thermal or optical properties.

Basic Information

Product Name	(2R)-3,3'Aβ,6',6',9'Aβ-Pentamethyl-3'A,4',5',5'Aα,6',7',8',9',9'A,9'Bα-Decahydrospiro[Furan-2(5H),2'(1'H)-Naphtho[2,1-B]Furan]-5-One
CAS No.	1235-78-5
Molecular Formula	C21H30O3
Molecular Weight	330.46 g/mol
Synonyms	(2R)-Pentamethyl-decahydrospiro[furan-2(5H),2'(1'H)-naphtho[2,1-b]furan]-5-one; Decahydrospiro[furan-2(5H),2'(1'H)-naphtho[2,1-b]furan]-5-one, 3,3',6,6',9'-pentamethyl-, (2R,3'aR,5'aS,6'S,9'aR,9'bS)-; Spiro[furan-2(5H),2'(1'H)-naphtho[2,1-b]furan]-5-one, decahydro-3,3',6,6',9'-pentamethyl-, (2R,3'aR,5'aS,6'S,9'aR,9'bS)-; (2R)-3,3',6,6',9'-Pentamethyldecahydrospiro[furan-2(5H),2'(1'H)-naphtho[2,1-b]furan]-5-one; CAS 1235-78-5
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.