Description

2-Methyl-4,5,8-Trichloroquinoline is a halogenated quinoline derivative, a versatile heterocyclic building block prized for its unique chemical reactivity and structural framework. This compound serves as a critical intermediate in the synthesis of complex molecules, particularly in the development of advanced materials and active pharmaceutical ingredients (APIs). It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce functionalized quinoline motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or cancer, where the quinoline core is a privileged scaffold.
• Agrochemical Synthesis: Used in the development of new generation pesticides and herbicides, leveraging the bioactivity of chlorinated quinoline structures.
• Material Science Research: Serves as a building block for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), or photoactive materials due to its electron-deficient aromatic system.
• Chemical Synthesis: Employed in organic chemistry research for cyclization reactions, cross-coupling reactions, and as a substrate for further functionalization.
• Dye and Pigment Intermediate: Acts as a precursor in the manufacture of specialized quinoline-based dyes and colorants.

Basic Information

Product Name	2-Methyl-4,5,8-Trichloroquinoline
CAS No.	1203-36-7
Molecular Formula	C10H6Cl3N
Molecular Weight	246.52 g/mol
Synonyms	4,5,8-Trichloro-2-methylquinoline; 2-Methyl-4,5,8-trichloroquinoline; Quinoline, 4,5,8-trichloro-2-methyl-; 4,5,8-Trichloro-2-methyl-quinoline; 2-Methyl-4,5,8-trichloro-quinoline
EINECS	Contact for details

Quality Control

Our 2-Methyl-4,5,8-Trichloroquinoline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided and available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.