Description

2,2',4',5'-Tetrachloroacetophenone is a specialized chlorinated aromatic ketone of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research institutions and industrial manufacturers engaged in creating active ingredients, fine chemicals, and functional materials that require a precisely substituted aromatic core.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those with halogenated aromatic structures.
• Agrochemical Synthesis: Used in the research and production of herbicides, pesticides, and fungicides where the tetrachloroacetophenone moiety imparts specific biological activity.
• Fine Chemical Production: Acts as a building block for dyes, pigments, and other specialty organic compounds requiring chlorinated aromatic ketones.
• Chemical Research: Valuable reagent in academic and industrial R&D for studying electrophilic aromatic substitution and ketone chemistry.
• Material Science: Potential intermediate in the synthesis of monomers or additives for advanced polymers and functional materials.

Basic Information

Product Name	2,2',4',5'-Tetrachloroacetophenone
CAS No.	1201-42-9
Molecular Formula	C8H4Cl4O
Molecular Weight	259.93 g/mol
Synonyms	2,2',4',5'-Tetrachloroacetophenone; 1-(2,4,5-Trichlorophenyl)-2-chloroethanone; 2',4',5'-Tetrachloroacetophenone; NSC 406908; Ethanone, 2-chloro-1-(2,4,5-trichlorophenyl)-; Acetophenone, 2,2',4',5'-tetrachloro-
EINECS	214-871-7

Quality Control

Our 2,2',4',5'-Tetrachloroacetophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support custom purity requirements for specific R&D or production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	90 - 94 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.