Description

6-Azaspiro[2.5]Octane-5,7-Dione CAS NO 1194-45-2 is a specialized heterocyclic building block featuring a unique spirocyclic structure. This compound is of significant value in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in scaffold hopping and structure-activity relationship (SAR) studies to explore new chemical space.
• Agrochemical Synthesis: Serves as a precursor in the design and synthesis of new herbicides or insecticides with novel modes of action.
• Chemical Biology Probes: Utilized in the synthesis of tool compounds for studying biological pathways and protein function.
• Academic & R&D Laboratories: Employed in methodological research and the synthesis of complex natural product analogs.
• Custom Synthesis & Contract Manufacturing: A critical starting material for the production of bespoke fine chemicals and advanced intermediates.

Basic Information

Product Name	6-Azaspiro[2.5]Octane-5,7-Dione
CAS No.	1194-45-2
Molecular Formula	C7H9NO2
Molecular Weight	139.15 g/mol
Synonyms	6-Azaspiro[2.5]octane-5,7-dione; 1-Azaspiro[2.5]octane-2,4-dione; 2,4-Dioxo-1-azaspiro[2.5]octane; 1-Azabicyclo[3.1.0]hexane-2,4-dione; 6-Azaspiro(2.5)octane-5,7-dione; Spiro[cyclopropane-1,1'-pyrrolidine]-2',4'-dione
EINECS	Contact for details

Quality Control

Our 6-Azaspiro[2.5]Octane-5,7-Dione is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.