Description

Bicyclo[2.2.2]Octan-1-Amine, 4-Methyl-, Hydrochloride (1:1) is a high-purity, functionalized bicyclic amine hydrochloride salt, a versatile building block in advanced organic synthesis. This compound is valued for its rigid, three-dimensional scaffold, which is crucial for modulating the physicochemical properties and biological activity of target molecules. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block or a conformational constraint in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where its bicyclic structure can contribute to unique modes of action.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and specialty chemicals requiring rigid, amine-functionalized components.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new chemical spaces in discovery programs.

Basic Information

Product Name	Bicyclo[2.2.2]Octan-1-Amine, 4-Methyl-, Hydrochloride (1:1)
CAS No.	1194-43-0
Molecular Formula	C9H17N·HCl
Molecular Weight	175.70 g/mol
Synonyms	4-Methylbicyclo[2.2.2]octan-1-amine hydrochloride; 1-Amino-4-methylbicyclo[2.2.2]octane hydrochloride; 4-Methyl-1-aminobicyclo[2.2.2]octane HCl; 4-Methyl-2-azabicyclo[2.2.2]octane hydrochloride (tautomer); 4-Methylbicyclo[2.2.2]oct-1-ylamine hydrochloride; 1-Bicyclo[2.2.2]octanamine, 4-methyl-, hydrochloride
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.2]Octan-1-Amine, 4-Methyl-, Hydrochloride (1:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay, impurities, and other critical parameters are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.