Description

1-Aminobicyclo[2.2.2]octane is a rigid, cage-like primary amine characterized by its unique bicyclic structure, which imparts significant steric hindrance and basicity. This compound serves as a valuable and versatile building block and ligand precursor in advanced organic synthesis and materials science. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with specific structural and electronic properties.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring rigid, three-dimensional amine scaffolds for receptor binding.
• Catalyst & Ligand Synthesis: Acts as a precursor for creating specialized ligands in transition metal catalysis, leveraging its strong electron-donating and steric properties.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and plant growth regulators where its structural motif can enhance biological activity.
• Polymer Modification: Utilized as a monomer or cross-linking agent to introduce amine functionality and rigidity into polymer backbones for advanced materials.
• Corrosion Inhibitor Formulation: Incorporated into specialty formulations where its amine group can act as a neutralizing agent and film-forming compound.
• Academic & R&D: A key reagent in organic chemistry research for studying reaction mechanisms, steric effects, and developing new synthetic methodologies.

Basic Information

Product Name	1-Aminobicyclo[2.2.2]octane
CAS No.	1193-42-6
Molecular Formula	C8H15N
Molecular Weight	125.21 g/mol
Synonyms	2.2.2-Bicyclooctan-1-amine; Bicyclo[2.2.2]octan-1-amine; 1-Azabicyclo[2.2.2]octane (common misnomer for the amine); 1-ABC-O; 1-Aminoquinuclidine; Quinuclidin-1-amine; 1-Amino-2.2.2-bicyclooctane; 1-BCOA
EINECS	214-783-5

Quality Control

Our 1-Aminobicyclo[2.2.2]octane is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay and impurity profiles to meet your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.