Description

Cyclobutanone, 2-Bromo-2-Methyl- is a specialized brominated cyclobutanone derivative, a valuable building block in advanced organic synthesis. This compound matters for its unique sterically hindered α-bromo ketone structure, which makes it a versatile precursor for constructing complex, strained ring systems and introducing functional groups. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly those containing cyclobutane or spirocyclic ring systems.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with unique modes of action.
• Material Science: Serves as a monomer or cross-linking agent in the research of specialty polymers with specific thermal or mechanical properties.
• Organic Synthesis Building Block: Employed in ring-expansion reactions, nucleophilic substitution reactions, and as a precursor for other functionalized cyclobutanes.
• Academic & R&D: Utilized in university and institutional laboratories for methodological development and exploring new chemical spaces.
• Ligand & Catalyst Development: Acts as a precursor for chiral ligands or catalysts used in asymmetric synthesis.

Basic Information

Product Name	Cyclobutanone, 2-Bromo-2-Methyl-
CAS No.	1192-12-7
Molecular Formula	C5H7BrO
Molecular Weight	163.01 g/mol
Synonyms	2-Bromo-2-methylcyclobutanone; 2-Methyl-2-bromocyclobutanone; α-Bromo-α-methylcyclobutanone; Bromomethyl cyclobutanone; 2-Bromo-2-methyl-cyclobutan-1-one
EINECS	214-764-5

Quality Control

Our Cyclobutanone, 2-Bromo-2-Methyl- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.