Description

Mevalonic Acid-5-Phosphate is a key phosphorylated intermediate in the essential mevalonate pathway for isoprenoid biosynthesis. This compound matters as a critical building block for the production of sterols, terpenes, and other vital biomolecules, making it indispensable for research and development in metabolic studies. It is primarily needed by biotechnology, pharmaceutical, and academic research sectors for enzyme studies, pathway analysis, and the synthesis of complex natural products.

Application

• Biochemical Research: Used as a standard and substrate in enzymatic assays to study the activity of phosphomevalonate kinase and downstream enzymes in the isoprenoid pathway.
• Metabolic Pathway Analysis: A crucial intermediate for investigating the regulation and flux of the mevalonate pathway in various organisms.
• Pharmaceutical Development: Serves as a precursor in research focused on developing drugs that target cholesterol biosynthesis or other isoprenoid-dependent processes.
• Enzyme Kinetics & Characterization: Employed to determine kinetic parameters and inhibition profiles of key enzymes like mevalonate kinase and diphosphomevalonate decarboxylase.
• Synthesis of Isotopically Labeled Compounds: Used in the preparation of 13C or 2H-labeled intermediates for advanced metabolic tracing and NMR studies.
• Nutritional & Cosmetic Science: Investigated for its role in the biosynthesis of coenzyme Q10 and other bioactive isoprenoids with potential health and cosmetic applications.

Basic Information

Product Name	Mevalonic Acid-5-Phosphate
CAS No.	1189-94-2
Molecular Formula	C6H13O8P
Molecular Weight	244.14 g/mol
Synonyms	(R)-Mevalonic Acid 5-Phosphate; (R)-5-Phosphomevalonic Acid; Mevalonate 5-Phosphate; 5-Phosphomevalonate; (3R)-3,5-Dihydroxy-3-methylpentanoic Acid 5-(Dihydrogen Phosphate); 3-Methyl-3,5-dihydroxypentanoic Acid 5-Phosphate; M5P; Phosphomevalonic Acid
EINECS	214-714-9

Quality Control

Our Mevalonic Acid-5-Phosphate is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-purity standards suitable for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.