Description

Diethyl(3-Bromopropyl)Phosphonate is a versatile organophosphorus compound featuring a reactive bromopropyl group, making it a valuable bifunctional building block in synthetic chemistry. Its primary commercial value lies in its role as a key intermediate for the synthesis of complex molecules, particularly through Horner-Wadsworth-Emmons (HWE) olefination reactions. This product is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to construct carbon-carbon double bonds and introduce phosphonate functionalities.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing α,β-unsaturated esters, amides, and nitriles via HWE reactions.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require specific alkene linkages.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing phosphonate-based ligands used in metal catalysis and coordination chemistry.
• Material Science: Employed in the creation of functionalized polymers, flame retardants, and surface-modifying agents.
• Chemical Research: A fundamental reagent in academic and industrial laboratories for method development and exploring new synthetic pathways.
• Fine Chemical Production: Intermediate for manufacturing flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	Diethyl(3-Bromopropyl)Phosphonate
CAS No.	1186-10-3
Molecular Formula	C7H16BrO3P
Molecular Weight	259.08 g/mol
Synonyms	(3-Bromopropyl)phosphonic Acid Diethyl Ester; Diethyl 3-Bromopropylphosphonate; 3-Bromopropylphosphonic Acid Diethyl Ester; Diethyl (3-Bromopropyl)Phosphonate; (3-Bromopropyl)phosphonic Acid Diethyl Ester; Diethyl P-(3-Bromopropyl)phosphonate; BRPEP; 1186-10-3
EINECS	214-672-5

Quality Control

Our Diethyl(3-Bromopropyl)Phosphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC, NMR, and titration methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed and moisture-sensitive.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.4680 - 1.4720
Density (20°C)	1.30 - 1.35 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.