Description

(R,S)-n-Nitrosoanabasine is a nitrosated alkaloid derivative of anabasine, a compound found in tobacco plants. This chemical is of significant interest in research and development, particularly for its role as a precursor or model compound in the study of nitrosamine formation and behavior. It serves as a critical reference standard and intermediate for scientists and manufacturers in the pharmaceutical, analytical chemistry, and toxicology sectors who require high-purity, well-characterized nitrosamine compounds for their work.

Application

• Analytical Reference Standard: Used as a certified reference material (CRM) for the calibration of analytical instruments and the validation of methods in nitrosamine testing, crucial for pharmaceutical quality control.
• Pharmaceutical Research: Acts as a key intermediate or model compound in the research and development of new therapeutic agents and in studies investigating drug metabolism and stability.
• Toxicological Studies: Employed in laboratory research to study the formation, metabolism, and carcinogenic potential of tobacco-specific nitrosamines (TSNAs) and related compounds.
• Chemical Synthesis: Serves as a specialized building block or precursor in the synthesis of more complex molecules for research purposes in organic and medicinal chemistry.
• Regulatory Compliance Testing: Essential for laboratories performing testing to comply with stringent regulatory guidelines (e.g., FDA, EMA) regarding nitrosamine impurities in pharmaceuticals and consumer products.
• Academic Research: Used in universities and research institutes for fundamental studies in chemical reactivity, environmental chemistry, and analytical method development.

Basic Information

Product Name	(R,S)-n-Nitrosoanabasine
CAS No.	1133-64-8
Molecular Formula	C10H13N3O
Molecular Weight	191.23 g/mol
Synonyms	N-Nitrosoanabasine; 1-Nitroso-2-(3-pyridyl)piperidine; 2-(3-Pyridyl)-1-nitrosopiperidine; 3-(1-Nitroso-2-piperidyl)pyridine; N-Nitrosoanatabine (common misidentification); Anabasine, N-nitroso-; TSNA (Tobacco-Specific Nitrosamine) reference compound
EINECS	214-492-5

Quality Control

Every batch of (R,S)-n-Nitrosoanabasine is produced and analyzed under strict quality management protocols. Our products undergo rigorous identity confirmation, purity assay, and impurity profiling using advanced analytical techniques such as HPLC, GC, and NMR to ensure compliance with research and reference standard requirements. A comprehensive Certificate of Analysis (COA), detailing all test results and traceable to reference standards, is provided with each shipment to guarantee batch-to-batch consistency and data integrity for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation and degradation. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95% (Research Grade)
Purity (HPLC)	≥ 98% (Analytical Standard)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.