Description

1-(1-Benzothiophen-5-Yl)-2-Bromo-1-Ethanone is a specialized brominated ketone derivative of benzothiophene, serving as a key synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex heterocyclic scaffolds, particularly in the development of novel pharmacologically active molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for targeted synthesis and molecular discovery programs.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs), particularly those containing benzothiophene cores.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that leverage the benzothiophene moiety for biological activity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the research of organic semiconductors, conductive polymers, and advanced organic materials.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and tool compounds for studying biological pathways and enzyme functions.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for methodological studies and exploratory synthesis projects.
• Custom Synthesis & Scale-Up: A starting material for contract manufacturing organizations (CMOs) engaged in custom synthesis and pilot-scale production of specialty chemicals.

Basic Information

Product Name	1-(1-Benzothiophen-5-Yl)-2-Bromo-1-Ethanone
CAS No.	1131-87-9
Molecular Formula	C10H7BrOS
Molecular Weight	255.13 g/mol
Synonyms	2-Bromo-1-(5-benzothienyl)ethanone; 5-Acetylbenzothiophene 2-bromo derivative; 1-(Benzo[b]thiophen-5-yl)-2-bromoethanone; α-Bromo-5-acetylbenzothiophene; 2-Bromo-1-(1-benzothiophen-5-yl)ethan-1-one; 5-(2-Bromoacetyl)benzothiophene; 1131-87-9; Bromo(5-benzothienyl)methanone
EINECS	Contact for details

Quality Control

Our 1-(1-Benzothiophen-5-Yl)-2-Bromo-1-Ethanone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.