Description

1-Bromo-2,4,6-Trimethoxybenzene is a versatile brominated aromatic building block characterized by its three methoxy substituents, which significantly influence its reactivity and electronic properties. This compound is a critical intermediate in advanced organic synthesis, enabling the construction of complex molecules for high-value applications. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and materials science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in constructing complex heterocycles and functionalized aromatic cores.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its halogen and methoxy groups for structural diversification.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and advanced polymers where its bromine atom allows for further functionalization via cross-coupling reactions.
• Chemical Research & Development: A valuable reagent for method development in organic chemistry, including studies on electrophilic aromatic substitution and protecting group strategies.

Basic Information

Product Name	1-Bromo-2,4,6-Trimethoxybenzene
CAS No.	1131-40-4
Molecular Formula	C9H11BrO3
Molecular Weight	247.09 g/mol
Synonyms	2,4,6-Trimethoxybromobenzene; 2-Bromo-1,3,5-trimethoxybenzene; Benzene, 1-bromo-2,4,6-trimethoxy-; 1,3,5-Trimethoxy-2-bromobenzene; Bromomesitylene trimethyl ether (related); NSC 406908
EINECS	214-456-8

Quality Control

Our 1-Bromo-2,4,6-Trimethoxybenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and melting point determination, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support custom synthesis and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.