Description

Ethyl L-Alaninate Hydrochloride is a protected amino acid derivative, specifically the ethyl ester hydrochloride salt of L-alanine. This compound is a crucial chiral building block in organic synthesis, offering a reactive ester group and a protected amine for controlled peptide coupling and molecular construction. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of peptides, active pharmaceutical ingredients (APIs), and fine chemicals. Its high purity and defined stereochemistry are essential for ensuring the quality and efficacy of the final synthesized products.

Application

• Peptide Synthesis: Serves as a key chiral intermediate for the controlled, stepwise construction of custom peptides and peptidomimetics in solid-phase and solution-phase synthesis.
• Pharmaceutical Intermediates: Used as a building block in the research and production of active pharmaceutical ingredients (APIs) and prodrugs that incorporate the alanine moiety.
• Biochemical Research: Employed in enzymatic studies, metabolic pathway investigations, and as a substrate or standard in analytical method development.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material for the synthesis of non-natural amino acids and other enantiomerically pure compounds.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, agrochemicals, and advanced materials requiring specific stereochemistry.

Basic Information

Product Name	Ethyl L-Alaninate Hydrochloride
CAS No.	1115-59-9
Molecular Formula	C5H12ClNO2
Molecular Weight	153.61 g/mol
Synonyms	L-Alanine ethyl ester hydrochloride; (S)-2-Aminopropanoic acid ethyl ester hydrochloride; Ethyl (S)-2-aminopropanoate hydrochloride; Alanine ethyl ester HCl; H-Ala-OEt·HCl; Ethyl L-2-aminopropionate hydrochloride; L-α-Aminopropionic acid ethyl ester hydrochloride
EINECS	214-232-6

Quality Control

Our Ethyl L-Alaninate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and synthesis. Key parameters such as chiral purity (enantiomeric excess), chemical purity (by HPLC), and identity (by IR and NMR) are rigorously verified. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent hydrolysis and degradation. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	+15.0° to +18.0° (c=1 in H2O)
Melting Point	76°C - 80°C
Heavy Metals (as Pb)	≤20 ppm
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.