Description

Ethyl (Triphenylphosphoranylidene)Acetate is a versatile Wittig reagent widely used in organic synthesis. This compound is crucial for the formation of carbon-carbon double bonds, specifically in the synthesis of α,β-unsaturated esters. It is an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to create complex olefinic structures with high stereoselectivity and yield.

Application

• Pharmaceutical Intermediates: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating unsaturated ester moieties found in various drug candidates.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require specific alkene functionalities.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, fragrances, and dyes where precise olefination is required.
• Material Science Research: Serves as a precursor in the development of novel polymers, liquid crystals, and organic electronic materials.
• Academic & R&D Laboratories: A staple reagent for method development and exploratory organic synthesis in university and industrial research settings.
• Peptide Modification: Utilized in the synthesis of dehydroamino acid derivatives, which are important in peptide chemistry and biochemistry.

Basic Information

Product Name	Ethyl (Triphenylphosphoranylidene)Acetate
CAS No.	1099-45-2
Molecular Formula	C22H21O2P
Molecular Weight	348.38 g/mol
Synonyms	(Carbethoxymethylene)triphenylphosphorane; Ethyl 2-(triphenylphosphoranylidene)acetate; Ethyl (triphenylphosphoranylidene)ethanoate; Ethyl 2-(triphenyl-λ5-phosphanylidene)acetate; Wittig reagent - Ethyl (triphenylphosphoranylidene)acetate; ETPA; Acetic acid, 2-(triphenylphosphoranylidene)-, ethyl ester
EINECS	214-158-3

Quality Control

Our Ethyl (Triphenylphosphoranylidene)Acetate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and performance consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting key parameters such as assay, melting point, and spectroscopic data. Our quality commitment ensures the reagent meets the high standards required for sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature, the container should be kept in the original packaging or an amber vessel. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	156 - 160 °C
Loss on Drying	≤ 0.5%
Solubility	Soluble in common organic solvents (e.g., THF, DCM, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.