Description

2-(Tritylthio)Ethanamine,2-[(Triphenylmethyl)Thio]- Ethanamine is a specialized organosulfur compound featuring a trityl-protected thioether linkage to an ethanamine moiety. This molecular architecture makes it a valuable protecting group reagent and a versatile synthetic intermediate in advanced organic synthesis. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers for the controlled construction of complex molecules, particularly in peptide chemistry and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those requiring sulfur-containing functional groups.
• Peptide Synthesis: Used as a protecting group for thiol-containing amino acids (e.g., cysteine) during solid-phase and solution-phase peptide synthesis to prevent unwanted side reactions.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Chemical Biology Research: Employed in the design and synthesis of biochemical probes and molecular tools for studying enzyme mechanisms and protein interactions.
• Material Science: Potential intermediate in the synthesis of functionalized polymers and advanced materials with specific surface properties.

Basic Information

Product Name	2-(Tritylthio)Ethanamine,2-[(Triphenylmethyl)Thio]- Ethanamine
CAS No.	1095-85-8
Molecular Formula	C21H21NS
Molecular Weight	319.46 g/mol
Synonyms	2-(Triphenylmethylthio)ethanamine; 2-[(Triphenylmethyl)thio]ethanamine; N-(2-Mercaptoethyl)tritylamine; Tritylthioethylamine; Ethanamine, 2-[(triphenylmethyl)thio]-; 2-(Tritylthio)ethylamine; S-Trityl-2-aminoethanethiol; 1095-85-8
EINECS	214-142-1

Quality Control

Our 2-(Tritylthio)Ethanamine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and production use. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture and atmospheric oxygen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.