Description

Diethyl (2-Oxobutyl)Phosphonate is a high-purity organophosphorus compound that serves as a versatile building block in organic synthesis. Its primary value lies in its role as a key reagent for the Horner-Wadsworth-Emmons (HWE) olefination reaction, enabling the efficient synthesis of α,β-unsaturated carbonyl compounds. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A critical reagent for constructing α,β-unsaturated ketones and esters, which are common scaffolds in active pharmaceutical ingredients (APIs).
• Agrochemical Production: Used in the synthesis of advanced pesticide and herbicide molecules that require specific alkene functionalities.
• Fine Chemical Manufacturing: Employed in the production of specialty chemicals, flavors, fragrances, and advanced materials via olefination reactions.
• Academic & Industrial R&D: A staple reagent in research laboratories for method development and exploring new synthetic pathways involving carbon-carbon double bond formation.
• Material Science Precursor: Can be utilized in the synthesis of functionalized organic molecules for advanced polymeric or electronic materials.

Basic Information

Product Name	Diethyl (2-Oxobutyl)Phosphonate
CAS No.	1067-73-8
Molecular Formula	C8H17O4P
Molecular Weight	208.19 g/mol
Synonyms	Diethyl (2-oxobutyl)phosphonate; (2-Oxobutyl)phosphonic acid diethyl ester; Diethyl 2-oxobutylphosphonate; Butan-2-one-1-diethylphosphonate; 1-Diethoxyphosphoryl-2-butanone; Acetylpropionylphosphonate diethyl ester; Diethyl (1-oxobutan-2-yl)phosphonate; (2-Oxobutyl)-phosphonic acid diethyl ester
EINECS	213-923-6

Quality Control

Our Diethyl (2-Oxobutyl)Phosphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure a typical purity of ≥96% and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.430 - 1.440
Density (20°C)	1.08 - 1.12 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.