Description

Triphenylphosphine Dibromide is a versatile and highly reactive brominating agent and catalyst used in organic synthesis. Its primary value lies in its ability to facilitate key transformations, such as the conversion of alcohols to alkyl bromides and the synthesis of α-bromoketones, with high efficiency and selectivity. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries, where precise bromination is a critical synthetic step. Triphenylphosphine Dibromide CAS NO 1034-39-5 is a fundamental reagent for building complex molecular architectures.

Application

• Bromination Reagent: Key for the Appel reaction, converting primary and secondary alcohols into corresponding alkyl bromides under mild conditions.
• Pharmaceutical Intermediate Synthesis: Used in the preparation of active pharmaceutical ingredients (APIs) and complex drug candidates requiring bromo-functionalization.
• Agrochemical Manufacturing: Employed in the synthesis of herbicides, fungicides, and insecticides where bromine atoms are integral to biological activity.
• Specialty Chemical Production: Facilitates the synthesis of fine chemicals, dyes, and photoinitiators.
• α-Bromoketone Preparation: Effective reagent for the bromination of ketones at the α-position, a crucial step in heterocyclic chemistry.
• Polymer Chemistry: Acts as a catalyst or intermediate in the synthesis of flame retardants and functional polymers.
• Research & Development: A staple reagent in academic and industrial R&D labs for exploring new synthetic methodologies.

Basic Information

Product Name	Triphenylphosphine Dibromide
CAS No.	1034-39-5
Molecular Formula	C18H15Br2P
Molecular Weight	422.10 g/mol
Synonyms	Phosphine, dibromotriphenyl-; Dibromotriphenylphosphorane; Triphenylphosphorane dibromide; P,P,P-Triphenylphosphine dibromide; NSC 154105; TPPBr2; Appel's Salt (related reagent)
EINECS	213-844-2

Quality Control

Our Triphenylphosphine Dibromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. We provide comprehensive analytical data, including purity assay and impurity profile, to support your quality assurance requirements. Certificates of Analysis (COA) detailing specifications and test results are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	228 - 232 °C
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.