Description

(+/-)-Ha-966 CAS NO 1003-51-6 is a high-purity, non-selective NMDA receptor antagonist used as a critical research chemical and pharmaceutical intermediate. This compound is valued for its ability to modulate glutamatergic neurotransmission, making it essential for neurological and pharmacological studies. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on central nervous system (CNS) drug discovery and development.

Application

• Neuroscience Research: A key tool compound for studying the role of NMDA receptors in synaptic plasticity, learning, memory, and neurodegenerative disease models.
• Pharmacological Studies: Used in vitro and in vivo to investigate excitotoxicity, neuroprotection, and the mechanisms of action of potential CNS therapeutics.
• Pharmaceutical Intermediate: Serves as a building block in the synthetic pathways for more complex neuroactive molecules and candidate drugs.
• Biochemical Assay Development: Employed as a standard or reference material in high-throughput screening (HTS) assays targeting ionotropic glutamate receptors.
• Academic Research: Fundamental research in universities and institutes exploring glutamatergic signaling pathways and receptor physiology.

Basic Information

Product Name	(+/-)-Ha-966
CAS No.	1003-51-6
Molecular Formula	C4H9NO2
Molecular Weight	103.12 g/mol
Synonyms	HA-966; (±)-HA-966; 3-Amino-1-hydroxypyrrolidin-2-one; 1-Hydroxy-3-aminopyrrolidin-2-one; (RS)-HA-966; RGH-527; NMDA Receptor Antagonist HA-966; (±)-1-Hydroxy-3-aminopyrrolidin-2-one
EINECS	Contact for details

Quality Control

Our (+/-)-Ha-966 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.