Description

Acetamidine Base CAS NO 143-37-3 is a versatile organic compound belonging to the amidine class, serving as a crucial building block in advanced chemical synthesis. Its strong basicity and nucleophilic character make it an essential reagent for constructing heterocyclic cores and pharmaceutical intermediates. This high-purity chemical is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various nitrogen-containing heterocycles, including pyrimidines, triazines, and imidazoles, which are core structures in many APIs.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and plant growth regulators that require amidine functionality.
• Organic Synthesis Reagent: Acts as a strong, non-nucleophilic base and a versatile building block for introducing the amidine group into complex molecules.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new reaction pathways and creating novel chemical entities.
• Material Science: Potential monomer or modifier in the production of specialty polymers and resins.

Basic Information

Product Name	Acetamidine Base
CAS No.	143-37-3
Molecular Formula	C2H6N2
Molecular Weight	58.08 g/mol
Synonyms	Acetamidine; Ethanamidine; Acetimidamide; N-Ethanimidamide; Acetic acid amidine; Acetamidine free base; 1-Aminoethanimine; Acetamidine, 98%
EINECS	205-591-8

Quality Control

Our Acetamidine Base is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including purity assay and impurity profiling by HPLC, to ensure it meets exacting standards for research and industrial use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to specifications.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store in a cool, dry place, ideally at 15-25°C, under an inert atmosphere such as nitrogen or argon for long-term stability. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.