Description

N,n-Bis(2-Hydroxyethyl)Glycine Sodium Salt is a high-purity organic salt widely used as a buffering agent and complexing agent in biochemical and pharmaceutical applications. Its primary value lies in its excellent buffering capacity in the physiological pH range and its ability to chelate metal ions, which is critical for stabilizing sensitive biological systems. This product is essential for manufacturers and researchers in the biopharmaceutical, diagnostic, and cell culture media industries who require reliable, high-quality buffer components.

Application

• Biopharmaceutical Buffer: A key component in formulation buffers for monoclonal antibodies, vaccines, and other therapeutic proteins to maintain pH stability.
• Cell Culture Media: Used as a buffering agent in mammalian cell culture media to maintain optimal pH for cell growth and protein expression.
• Diagnostic Reagents: Employed in the formulation of clinical diagnostic kits and reagents where precise pH control is required.
• Biochemical Research: Serves as a buffering agent in electrophoresis, chromatography, and various enzymatic reaction mixtures.
• Metal Ion Chelation: Utilized to sequester trace metal ions that can catalyze degradation reactions in sensitive formulations.
• Cosmetic Formulations: Acts as a pH adjuster and stabilizer in high-end cosmetic and personal care products.

Basic Information

Product Name	N,n-Bis(2-Hydroxyethyl)Glycine Sodium Salt
CAS No.	139-41-3
Molecular Formula	C6H12NNaO5
Molecular Weight	201.15 g/mol
Synonyms	Bicine Sodium Salt; N,N-Bis(2-hydroxyethyl)glycine Sodium Salt; Sodium Bicine; 2,2'-Iminodiethanol Sodium Glycinate; BICINE Na; Bicine Na Salt; Sodium N,N-Bis(2-hydroxyethyl)glycinate; N,N-Bis(2-hydroxyethyl)aminoacetic Acid Sodium Salt
EINECS	205-365-5

Quality Control

Our N,n-Bis(2-Hydroxyethyl)Glycine Sodium Salt is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and performance. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing key parameters such as assay, pH, and heavy metal content to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product quality and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0 %
pH (1% Solution)	6.5 - 7.5
Loss on Drying	≤ 2.0 %
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1 %
Endotoxin (LAL)	< 0.25 EU/mg (for applicable grades)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.