Description

Methyl Acetoacetate CAS NO 105-45-3 is a versatile and high-purity organic ester, serving as a critical building block in advanced chemical synthesis. Its bifunctional structure, containing both a ketone and an ester group, makes it an essential reagent for producing high-value intermediates and fine chemicals. This product is indispensable for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality raw materials for complex synthesis.

Application

• Pharmaceutical Intermediates: Key starting material in the synthesis of active pharmaceutical ingredients (APIs), including antibiotics, vitamins (e.g., Vitamin B1), and heterocyclic compounds.
• Agrochemical Synthesis: Used in the production of pesticides, herbicides, and fungicides as a precursor for pyrazole and other heterocyclic structures.
• Fine Chemicals & Dyes: Acts as an acetoacetylating agent in the manufacture of pigments, dyes, and organic pigments like azo compounds.
• Flavor & Fragrance Ingredients: Employed in the synthesis of various fruity and sweet flavoring agents and aroma chemicals.
• Polymer & Resin Modifiers: Utilized as a cross-linking agent and monomer in specialty polymer production, including coatings and adhesives.
• Chemical Research & Development: A fundamental reagent in organic synthesis laboratories for Claisen condensations and Michael addition reactions.

Basic Information

Product Name	Methyl Acetoacetate
CAS No.	105-45-3
Molecular Formula	C5H8O3
Molecular Weight	116.12 g/mol
Synonyms	Acetoacetic Acid Methyl Ester; Methyl 3-Oxobutanoate; 3-Oxobutanoic Acid Methyl Ester; MAA; Methyl Acetoacetate Ester; Acetylacetic Acid Methyl Ester; Butanoic Acid, 3-Oxo-, Methyl Ester; Methyl β-Ketobutyrate
EINECS	203-299-8

Quality Control

Our Methyl Acetoacetate is manufactured under a stringent quality management system. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure it meets the high-purity standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to minimize moisture absorption and prevent volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 99.0%
Water Content (KF)	≤ 0.1%
Refractive Index (20°C)	1.418 - 1.422
Density (20°C)	1.075 - 1.080 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.