Description

Dihydroergotoxine Mesylate is a semi-synthetic ergot alkaloid derivative, also known as ergoloid mesylates. This compound is a critical active pharmaceutical ingredient (API) valued for its vasodilatory and metabolic-enhancing effects on cerebral neurons. It is primarily required by pharmaceutical manufacturers for the formulation of medications targeting age-related cognitive decline and cerebrovascular insufficiency. Our supply ensures high purity and batch-to-batch consistency for reliable production.

Application

• Pharmaceutical API: Primary use in the manufacture of prescription drugs for treating symptoms of senile dementia and age-related cognitive impairment.
• Vasodilator Formulations: Key ingredient in medications designed to improve cerebral blood flow and oxygen utilization in the brain.
• Neurological Therapeutics: Used in clinical research and development of therapies for cerebrovascular disorders and certain types of headaches.
• Generic Drug Production: Serves as the active component for generic versions of branded ergoloid mesylate medications.
• Reference Standard: High-purity grade suitable for use as an analytical reference standard in quality control laboratories.

Basic Information

Product Name	Dihydroergotoxine Mesylate
CAS No.	8067-24-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ergoloid Mesylates; Co-dergocrine Mesylate; Dihydroergocornine Mesylate; Dihydroergocristine Mesylate; Dihydroergocryptine Mesylate; Hydergine; Nicergoline Impurity; 9,10α-Dihydroergotoxine Methanesulfonate
EINECS	Contact for details

Quality Control

Our Dihydroergotoxine Mesylate is manufactured and tested under a GMP-compliant quality management system. Each batch undergoes rigorous analytical testing, including identification, assay, and impurity profiling, to ensure it meets stringent pharmaceutical standards. A comprehensive Certificate of Analysis (COA) documenting purity, related substances, and residual solvents is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water (Karl Fischer)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.