Description

N,n-Dimethyl-2-Chloroacetoacetamide is a versatile and reactive chloroacetylated amide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, offering both an electrophilic chloroacetyl group and an activated methylene unit for condensation reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for heterocyclic compounds and molecules with acetamide backbones.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, leveraging its reactive chloro and keto groups.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex organic dyes and colorants.
• Chemical Research & Development: A valuable reagent for constructing β-ketoamide frameworks and for studying nucleophilic substitution and condensation reactions.
• Polymer Chemistry: Can be utilized as a monomer or cross-linking agent in the synthesis of specialty polymers and resins.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing chelating ligands and organocatalysts.

Basic Information

Product Name	N,n-Dimethyl-2-Chloroacetoacetamide
CAS No.	5810-11-7
Molecular Formula	C6H10ClNO2
Molecular Weight	163.60 g/mol
Synonyms	2-Chloro-3-oxo-N,N-dimethylbutanamide; 2-Chloroacetoacetic Acid Dimethylamide; Chloroacetoacetic Acid Dimethylamide; N,N-Dimethyl-2-chloroacetoacetamide; 3-Oxo-N,N-dimethyl-2-chlorobutanamide; α-Chloroacetoacetic Acid Dimethylamide; Dimethylchloroacetoacetamide; Butanamide, 2-chloro-3-oxo-N,N-dimethyl-
EINECS	227-380-8

Quality Control

Our N,n-Dimethyl-2-Chloroacetoacetamide is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided and available upon request, supporting your GMP and ISO compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.