Description

tert-Butyl Acetoacetate is a versatile organic ester and a key acetoacetate derivative widely used as a chemical building block. Its value lies in its role as a protected form of acetoacetic acid, offering enhanced stability and reactivity for advanced synthesis. This compound is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable intermediates for complex molecule production.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for heterocyclic compounds and β-keto ester derivatives.
• Agrochemical Synthesis: Used in the manufacturing of pesticides, herbicides, and plant growth regulators where its ester group facilitates specific chemical transformations.
• Fine Chemical Production: Serves as a building block for dyes, pigments, flavors, and fragrances requiring acetoacetate functionality.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialized polymers and coatings.
• Chemical Research & Development: Employed in organic synthesis laboratories for developing new methodologies and novel compounds, including metal-organic frameworks (MOFs).
• Peptide Synthesis: Can be utilized as a protecting group reagent for specific amino acid side chains during peptide coupling processes.

Basic Information

Product Name	tert-Butyl Acetoacetate
CAS No.	1694-31-1
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	Acetoacetic Acid tert-Butyl Ester; 3-Oxobutanoic Acid 1,1-Dimethylethyl Ester; tert-Butyl 3-Oxobutanoate; Butanoic Acid, 3-Oxo-, 1,1-Dimethylethyl Ester; t-Butyl Acetoacetate; TBAA; BAA
EINECS	216-907-1

Quality Control

Our tert-Butyl Acetoacetate is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality protocols are designed to meet the stringent requirements of GMP and ISO standards where applicable, supporting our commitment to supply reliability for critical B2B applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (20°C)	1.418 - 1.422
Density (20°C)	0.980 - 1.010 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.