Appetite Suppressants and other Weight-loss Drugs

Appetite Suppressants and other Weight-loss Drugs

Appetite suppressants and other weight-loss drugs are pharmacological agents used to reduce caloric intake, enhance satiety, increase energy expenditure, or alter nutrient absorption. These medications include centrally acting appetite suppressants that modulate neurotransmitters such as serotonin, norepinephrine, or dopamine; peripheral agents that inhibit fat absorption; and metabolic enhancers that promote thermogenesis. They are prescribed for obesity management, metabolic syndrome, and weight control in patients at risk for cardiovascular disease or diabetes. Their mechanisms may involve reducing hunger signals, slowing gastric emptying, blocking pancreatic lipases, or improving insulin sensitivity. Because long-term therapy carries risks such as hypertension, mood disturbances, gastrointestinal effects, and potential dependency, medical supervision is essential. Despite limitations, these drugs offer significant benefits for patients requiring structured weight-management support.

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