Description

(αS)-3-[2-(2,6-DiMethylphenoxy)acetyl]-N-[(1S,3S,4S)-4-[[2-(2,6-diMethylphenoxy)acetyl]aMino]-3-hydroxy-5-phenyl-1-(phenylMethyl)pentyl]tetrahydro-α-(1-Methylethyl)-2-oxo-1(2H)-pyriMidineacetaMide is a sophisticated, high-purity chiral intermediate of significant interest in advanced pharmaceutical synthesis. Its complex, multi-functional structure makes it a critical building block for the development of novel therapeutic agents, particularly in research targeting complex biological pathways. This compound is essential for pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of proprietary drug candidates, where precise stereochemistry and high purity are non-negotiable.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Potential building block for compounds targeting enzymatic processes, given its peptide-like structural motifs.
• Preclinical Drug Development: Used in the synthesis of candidate molecules for pharmacological screening and structure-activity relationship (SAR) studies.
• Asymmetric Synthesis: Serves as a complex substrate or intermediate in stereoselective chemical transformations.
• Fine Chemical Production: Employed in contract manufacturing organizations (CMOs) for the custom synthesis of high-value, low-volume specialty chemicals.
• Academic Research: Utilized in university and institutional labs for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(αS)-3-[2-(2,6-DiMethylphenoxy)acetyl]-N-[(1S,3S,4S)-4-[[2-(2,6-diMethylphenoxy)acetyl]aMino]-3-hydroxy-5-phenyl-1-(phenylMethyl)pentyl]tetrahydro-α-(1-Methylethyl)-2-oxo-1(2H)-pyriMidineacetaMide
CAS No.	943250-66-6
Molecular Formula	C49H56N4O7
Molecular Weight	813.00 g/mol
Synonyms	Boc-D-Dap-OH; (2R)-2-({[(1,1-Dimethylethyl)oxy]carbonyl}amino)-3-aminopropanoic Acid; (R)-2-((tert-Butoxycarbonyl)amino)-3-aminopropanoic Acid; (R)-2-(Boc-amino)-3-aminopropionic Acid; H-D-Dap(Boc)-OH; (R)-3-Amino-2-((tert-butoxycarbonyl)amino)propanoic Acid; tert-Butyl (R)-(3-amino-1-carboxypropyl)carbamate; D-Dap(Boc)-OH
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under a strict quality management system. We employ state-of-the-art analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and chiral integrity meet the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.