Description

CARBAMIC ACID, N-[2-[(R)-(3-CHLOROPHENYL)[(3R)-1-[[[(2S)-2-(METHYLAMINO)-3-[(3R)-TETRAHYDRO-2H-PYRAN-3-YL]PROPYL]AMINO]CARBONYL]-3-PIPERIDINYL]METHOXY]ETHYL]-, METHYL ESTER is a sophisticated, high-purity chiral organic compound designed for advanced research and development. This molecule is of significant interest as a key intermediate or building block in the synthesis of novel pharmaceutical agents, particularly those targeting complex biological pathways. It is primarily utilized by medicinal chemists and process development scientists within the pharmaceutical and biotechnology industries. The precise stereochemistry and functional groups present in its structure make it a valuable asset for creating libraries of compounds with specific biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the research and development of new Active Pharmaceutical Ingredients (APIs), particularly for central nervous system (CNS) or metabolic disorder targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead drug candidates.
• Process Chemistry Development: Employed in scaling up synthetic routes for preclinical and clinical trial material production, where high stereochemical purity is paramount.
• Biochemical Probe Synthesis: Acts as a precursor for creating labeled or modified compounds used to study enzyme mechanisms or receptor interactions in biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized compounds under cGMP or non-GMP conditions as required.

Basic Information

Product Name	CARBAMIC ACID, N-[2-[(R)-(3-CHLOROPHENYL)[(3R)-1-[[[(2S)-2-(METHYLAMINO)-3-[(3R)-TETRAHYDRO-2H-PYRAN-3-YL]PROPYL]AMINO]CARBONYL]-3-PIPERIDINYL]METHOXY]ETHYL]-, METHYL ESTER
CAS No.	942142-51-0
Molecular Formula	C26H41ClN4O5
Molecular Weight	525.09 g/mol
Synonyms	Methyl N-[2-[(R)-(3-chlorophenyl)[(3R)-1-[[[(2S)-2-(methylamino)-3-[(3R)-oxan-3-yl]propyl]amino]carbonyl]-3-piperidinyl]methoxy]ethyl]carbamate; (3R)-N-[(2S)-2-(Methylamino)-3-[(3R)-tetrahydro-2H-pyran-3-yl]propyl]-1-[(R)-(3-chlorophenyl)(2-[[(methoxycarbonyl)amino]ethoxy)methyl]-3-piperidinecarboxamide; UNII-8J9VK66413; 8J9VK66413; A complex piperidine-pyran hybrid intermediate; Chiral carbamate derivative.
EINECS	Contact for details

Quality Control

This high-value intermediate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and purity suitable for pharmaceutical research. Our products undergo rigorous analytical testing, including HPLC, chiral HPLC, NMR, and MS, to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We can support development projects requiring compliance with ICH guidelines for impurities and stability.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This compound is likely hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.