Description

(7S)-7-[[(R)-5-Amino-5-carboxy-1-oxopentyl]amino]-7-methoxy-3-[[[6-amino-3-hydroxy-4-(L-alanyl-L-seryl-L-ornithyl-L-valylamino)-1,6-dioxohexyl]oxy]methyl]cepham-3-ene-4-carboxylic acid CAS NO 99313-75-4 is a complex, semi-synthetic cephalosporin derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel β-lactam antibiotics, offering a pathway to enhanced therapeutic agents. It is primarily utilized by pharmaceutical manufacturers and research institutions focused on developing next-generation antibacterial drugs to combat resistant pathogens.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of advanced-generation cephalosporin antibiotics.
• Antibacterial Drug Development: Used in R&D programs aimed at creating novel agents with improved spectra of activity against Gram-positive and Gram-negative bacteria.
• Mechanistic Studies: Serves as a reference standard or probe in biochemical studies investigating β-lactamase inhibition and penicillin-binding protein (PBP) interactions.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for complex antibiotic manufacturing.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry projects focused on antibiotic discovery.

Basic Information

Product Name	(7S)-7-[[(R)-5-Amino-5-carboxy-1-oxopentyl]amino]-7-methoxy-3-[[[6-amino-3-hydroxy-4-(L-alanyl-L-seryl-L-ornithyl-L-valylamino)-1,6-dioxohexyl]oxy]methyl]cepham-3-ene-4-carboxylic acid
CAS No.	99313-75-4
Molecular Formula	C36H56N10O15
Molecular Weight	868.90 g/mol
Synonyms	7-Methoxy Cephalosporin Derivative; Cephalosporin C Analogue; Antibiotic Intermediate 99313-75-4; (6R,7S)-7-[[(2R)-2-Amino-2-carboxyethyl]thioacetamido]-7-methoxy-3-[[(5S,6S)-5-amino-6-hydroxy-2-(L-alanyl-L-seryl-L-ornithyl-L-valylamino)hexanoyl]oxymethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid (related structural name); Advanced Cephalosporin Precursor
EINECS	Contact for details

Quality Control

Our production of this high-value pharmaceutical intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure structural identity and purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing assay, impurity profiles, and other critical parameters. Quality standards are aligned with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.