Description

(3R)-9-[4-O-[(2R,6S)-5,6-Dihydro-6-methyl-5-oxo-2H-pyran-2-yl]-2,6-dideoxy-β-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-3α,4aα,8,12bα-tetrahydroxy-3-methylbenz[a]anthracene-1,7,12(2H)-trione is a complex glycosylated anthraquinone derivative with significant biological activity. This compound matters as a high-value, structurally intricate intermediate or reference standard for advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development teams in the pharmaceutical and biotechnology industries, particularly those focused on oncology and antibiotic therapies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel anthracycline-class antibiotics and chemotherapeutic agents.
• Reference Standard: Used for analytical method development, validation, and quality control (QC/QA) in pharmaceutical manufacturing.
• Biochemical Research: Employed in studies investigating the mechanism of action of DNA-intercalating agents and topoisomerase inhibitors.
• Process Chemistry: Acts as a key intermediate for scaling up the production of complex active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in universities and research institutes for exploring new synthetic pathways and structure-activity relationships (SAR).

Basic Information

Item	Detail
Product Name	(3R)-9-[4-O-[(2R,6S)-5,6-Dihydro-6-methyl-5-oxo-2H-pyran-2-yl]-2,6-dideoxy-β-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-3α,4aα,8,12bα-tetrahydroxy-3-methylbenz[a]anthracene-1,7,12(2H)-trione
CAS No.	99260-66-9
Molecular Formula	C31H30O13
Molecular Weight	610.56 g/mol
Synonyms	9-[4-O-(5,6-Dihydro-6-methyl-5-oxo-2H-pyran-2-yl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-3,4a,8,12b-tetrahydroxy-3-methylbenz[a]anthracene-1,7,12(2H)-trione; Aclacinomycin T; 2H-Naphthacen-1,7,12-trione derivative; Glycosylated anthraquinone; Anthracycline analogue; 99260-66-9; Aclacinomycin T aglycone derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. Certificates of Analysis (COA) are available upon request, detailing batch-specific results. Production can adhere to cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, store at 2-8°C. The compound is light-sensitive and should be handled under inert atmosphere when appropriate to prevent degradation. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange-red powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.