Description

Butanoic acid, (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-12-(acetyloxy)-1,11,21-trihydroxy-17-(1R)-1-hydroxyethyl-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo21.3.1.13,7.111,15nonacos-8-en-25-yl is a highly complex, polycyclic macrolide derivative with a specific stereochemical configuration. This compound is of significant interest for its potential as a key intermediate or reference standard in advanced pharmaceutical research and development. It is primarily sought by specialty chemical manufacturers and R&D laboratories working in the fields of novel antibiotic discovery, targeted cancer therapies, and complex natural product synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel macrolide-based therapeutic agents.
• Research & Development: Used as a high-purity reference standard in analytical method development and biological activity studies.
• Antibiotic Research: Investigated for its potential as a precursor or analog in the development of new antimicrobial compounds.
• Oncology Drug Discovery: Employed in the synthesis and screening of complex molecules for targeted cancer treatments.
• Natural Product Chemistry: Acts as a model compound for studying the synthesis and modification of intricate natural product structures.
• Process Chemistry: Utilized in scaling up and optimizing synthetic routes for complex active pharmaceutical ingredients (APIs).

Basic Information

Item	Details
Product Name	Butanoic acid, (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-12-(acetyloxy)-1,11,21-trihydroxy-17-(1R)-1-hydroxyethyl-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-25-yl
CAS No.	97850-06-1
Molecular Formula	C44H62O17
Molecular Weight	862.96 g/mol
Synonyms	Lonomycin A; Lonomycin; Antibiotic 472A; Lonomycin A, Butanoic acid ester; (25S)-25-Butanoyloxy-12-O-acetyl-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-ene
EINECS	Contact for details

Quality Control

Our production of this high-value specialty chemical adheres to strict quality management systems. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or manufacturing protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The material is hygroscopic and should be handled in a dry environment to prevent degradation. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.