Description

(3R,3aα,5aα,9aβ,11aα,12R)-3β,3bβ-(Epoxymethano)-4α,12-dihydroxy-3a,3b,4,5,5a,6,7,8,9,9a,9bα,10,11,11a-tetradecahydro-6,6,9a-trimethylphenanthro[1,2-c]furan-1(3H)-one 4-acetate is a high-purity, complex diterpenoid derivative with a defined stereochemistry. This compound is of significant interest in advanced pharmaceutical research and development due to its intricate molecular framework, which serves as a key intermediate or reference standard for novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of bioactive natural product analogs and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research & development (R&D) laboratories for method development and compound identification.
• Medicinal Chemistry Research: Provides a sophisticated scaffold for structure-activity relationship (SAR) studies to explore new biological activities.
• Natural Product Synthesis: Acts as a key intermediate in the total or semi-synthesis of complex natural products and their derivatives.
• Biochemical Research: Utilized in studies investigating enzyme interactions or specific biological pathways due to its unique chemical structure.

Basic Information

Product Name	(3R,3aα,5aα,9aβ,11aα,12R)-3β,3bβ-(Epoxymethano)-4α,12-dihydroxy-3a,3b,4,5,5a,6,7,8,9,9a,9bα,10,11,11a-tetradecahydro-6,6,9a-trimethylphenanthro[1,2-c]furan-1(3H)-one 4-acetate
CAS No.	96999-35-8
Molecular Formula	C23H30O6
Molecular Weight	402.48 g/mol
Synonyms	4-Acetoxy derivative of the core diterpene; Phenanthrofuranone derivative; (3R,3aR,5aS,9aS,11aR,12R)-3-((3aR,5aS,9aS,11aR)-3b-((R)-Oxiran-2-yl)-4-hydroxy-3a,5a,9-trimethyl-2,3,3a,3b,4,5,5a,6,7,8,9,9a,9b,10,11,11a-hexadecahydro-1H-cyclopenta[a]phenanthren-7-yl)-4-hydroxy-6,6,9a-trimethyl-2,3,3a,3b,4,5,5a,6,7,8,9,9a,9b,10,11,11a-hexadecahydrophenanthro[1,2-c]furan-1-one (systematic variation); Diterpenoid acetate; CAS 96999-35-8.
EINECS	Contact for details

Quality Control

Our (3R,3aα,5aα,9aβ,11aα,12R)-3β,3bβ-(Epoxymethano)-4α,12-dihydroxy-3a,3b,4,5,5a,6,7,8,9,9a,9bα,10,11,11a-tetradecahydro-6,6,9a-trimethylphenanthro[1,2-c]furan-1(3H)-one 4-acetate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). A Certificate of Analysis (COA) detailing batch-specific results is provided to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.