Description

(5S)-2,5-Dihydro-5-methoxy-3-furancarboxylic acid (3aR,4R,6E,9S,10Z,11aR)-9-(acetyloxy)-2,3,3a,4,5,8,9,11a-octahydro-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester is a complex, high-purity sesquiterpene lactone derivative, serving as a critical advanced intermediate for pharmaceutical research and synthesis. Its intricate stereochemistry and functional groups make it a valuable scaffold for developing novel bioactive compounds, particularly in oncology and anti-inflammatory therapeutic areas. This product is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking reliable, high-quality building blocks.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, especially in complex natural product-derived therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique fused ring system and stereocenters.
• Process Chemistry Development: Serves as a reference standard or starting material for scaling up synthetic routes in pilot plants and commercial manufacturing.
• Biochemical Research: Potential use as a probe or inhibitor in studying biological pathways involving sesquiterpene lactone targets.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic Research: A valuable compound for universities and research institutes focusing on organic synthesis methodology and natural product chemistry.

Basic Information

Product Name	(5S)-2,5-Dihydro-5-methoxy-3-furancarboxylic acid (3aR,4R,6E,9S,10Z,11aR)-9-(acetyloxy)-2,3,3a,4,5,8,9,11a-octahydro-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester
CAS No.	95297-85-1
Molecular Formula	C23H30O7
Molecular Weight	418.48 g/mol
Synonyms	Parthenolide derivative; 3-Furancarboxylic acid, 2,5-dihydro-5-methoxy-, (3aR,4R,6E,9S,10Z,11aR)-9-(acetyloxy)-2,3,3a,4,5,8,9,11a-octahydro-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester, (5S)-; Acetylated parthenolide analog; Sesquiterpene lactone ester; (5S)-5-Methoxy-2,5-dihydrofuran-3-carboxylic acid ester
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and analyzed under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) that detail identity, purity, and impurity profiles, ensuring traceability and consistency for your critical research and development work. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated pharmaceutical development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound is compatible with strong acid/organic solvent environments but should be handled accordingly. Keep container tightly sealed when not in use to protect integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.