Description

N-[2-[(2R)-5α-(3,4-Dihydro-2,4-dioxopyrimidin-1(2H)-yl)tetrahydro-3β,4β-dihydroxyfuran-2α-yl]-N-[(3S,4S)-4-hydroxy-4-(5-hydroxypyridin-2-yl)-L-valyl]-L-glycyl]-L-homoserine is a complex, high-purity nucleoside amino acid conjugate designed for advanced pharmaceutical research and development. This compound is critical for applications requiring precise molecular structure and high biological activity, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on antiviral and anticancer drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel nucleoside analog prodrugs and targeted therapeutics.
• Antiviral Research: Used in the development and study of potential antiviral agents, particularly against DNA viruses.
• Oncology Drug Discovery: Employed as a precursor in the creation of chemotherapeutic compounds designed to interfere with cancer cell DNA synthesis.
• Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies to understand cellular pathways and mechanisms.
• Peptide-Nucleic Acid (PNA) Conjugate Synthesis: Utilized in the construction of advanced PNA oligomers for diagnostic and therapeutic applications.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in API manufacturing.

Basic Information

Product Name	N-[2-[(2R)-5α-(3,4-Dihydro-2,4-dioxopyrimidin-1(2H)-yl)tetrahydro-3β,4β-dihydroxyfuran-2α-yl]-N-[(3S,4S)-4-hydroxy-4-(5-hydroxypyridin-2-yl)-L-valyl]-L-glycyl]-L-homoserine
CAS No.	95259-50-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	L-Homoserine, N-[2-[(2R)-5α-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)tetrahydro-3β,4β-dihydroxy-2α-furanyl]-N-[(3S,4S)-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-L-valyl]-L-glycyl]-; 95259-50-0; Nucleoside-Amino Acid Conjugate; Uracil nucleoside amino acid derivative; Potential antiviral intermediate
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced and tested under strict quality management systems. We ensure compliance with the rigorous standards required for pharmaceutical research, including potential alignment with ICH guidelines. Comprehensive analytical testing, including HPLC for purity and identity confirmation, is performed. A detailed Certificate of Analysis (COA) documenting purity, related substances, and other critical parameters is provided with each shipment to guarantee traceability and consistency for your research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.